BDBM50012930 CHEMBL3261357

SMILES: O=C1NC(=O)\C(=C\c2ccc3OCOc3c2)C(=O)N1Cc1ccccc1

InChI Key: InChIKey=AIQAOCWPVYYIGL-ZSOIEALJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50012930 (CHEMBL3261357) Show SMILES O=C1NC(=O)\C(=C\c2ccc3OCOc3c2)C(=O)N1Cc1ccccc1 Show InChI InChI=1S/C19H14N2O5/c22-17-14(8-13-6-7-15-16(9-13)26-11-25-15)18(23)21(19(24)20-17)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,20,22,24)/b14-8-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Innsbruck Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant PKCepsilon (unknown origin)-MBP-tagged RACK2 interaction after 1 hr by ELISA-based assay relative to untreated control				J Med Chem 57: 3235-46 (2014) Article DOI: 10.1021/jm401605c BindingDB Entry DOI: 10.7270/Q2028T25
					More data for this Ligand-Target Pair