BDBM50013186 (Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-ylmethyl]-2-hydroxy-2-phenyl-acetamide::CHEMBL140974

SMILES: OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1

InChI Key: InChIKey=UVSPWLMLXNJJLO-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50013186   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50013186 ((Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-...) Show SMILES OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1 |c:16| Show InChI InChI=1S/C24H22FN3O2/c25-20-12-6-4-10-18(20)22-19-11-5-7-13-21(19)26-14-17(28-22)15-27-24(30)23(29)16-8-2-1-3-9-16/h1-13,17,23,26,29H,14-15H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to Cholecystokinin type A receptor in rat pancreas				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50013186 ((Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-...) Show SMILES OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1 |c:16| Show InChI InChI=1S/C24H22FN3O2/c25-20-12-6-4-10-18(20)22-19-11-5-7-13-21(19)26-14-17(28-22)15-27-24(30)23(29)16-8-2-1-3-9-16/h1-13,17,23,26,29H,14-15H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50013186 ((Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-...) Show SMILES OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1 |c:16| Show InChI InChI=1S/C24H22FN3O2/c25-20-12-6-4-10-18(20)22-19-11-5-7-13-21(19)26-14-17(28-22)15-27-24(30)23(29)16-8-2-1-3-9-16/h1-13,17,23,26,29H,14-15H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissues				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50013186 ((Diastereomer)-N-[5-(2-Fluoro-phenyl)-2,3-dihydro-...) Show SMILES OC(C(=O)NCC1CNc2ccccc2C(=N1)c1ccccc1F)c1ccccc1 |c:16| Show InChI InChI=1S/C24H22FN3O2/c25-20-12-6-4-10-18(20)22-19-11-5-7-13-21(19)26-14-17(28-22)15-27-24(30)23(29)16-8-2-1-3-9-16/h1-13,17,23,26,29H,14-15H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissues				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair