BDBM50013187 2-Fluoro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-ylmethyl]-benzamide::CHEMBL139615

SMILES: CN1C(CNC(=O)c2ccccc2F)CN=C(c2ccccc2F)c2ccccc12

InChI Key: InChIKey=YAOQWBSTVZSGGB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50013187 (2-Fluoro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihyd...) Show SMILES CN1C(CNC(=O)c2ccccc2F)CN=C(c2ccccc2F)c2ccccc12 |t:16| Show InChI InChI=1S/C24H21F2N3O/c1-29-16(15-28-24(30)18-9-3-6-12-21(18)26)14-27-23(17-8-2-5-11-20(17)25)19-10-4-7-13-22(19)29/h2-13,16H,14-15H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig brain tissues				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50013187 (2-Fluoro-N-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihyd...) Show SMILES CN1C(CNC(=O)c2ccccc2F)CN=C(c2ccccc2F)c2ccccc12 |t:16| Show InChI InChI=1S/C24H21F2N3O/c1-29-16(15-28-24(30)18-9-3-6-12-21(18)26)14-27-23(17-8-2-5-11-20(17)25)19-10-4-7-13-22(19)29/h2-13,16H,14-15H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas				J Med Chem 33: 450-5 (1990) BindingDB Entry DOI: 10.7270/Q26M35TN
					More data for this Ligand-Target Pair