BDBM50013280 5-(2-Guanidino-thiazol-4-yl)-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL357482

SMILES: CCOC(=O)c1cc([nH]c1C)-c1csc(N=C(N)N)n1

InChI Key: InChIKey=CSGVCYAMCSWQBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1/beta chain (Homo sapiens (Human))	BDBM50013280 (5-(2-Guanidino-thiazol-4-yl)-2-methyl-1H-pyrrole-3...) Show SMILES CCOC(=O)c1cc([nH]c1C)-c1csc(N=C(N)N)n1 Show InChI InChI=1S/C12H15N5O2S/c1-3-19-10(18)7-4-8(15-6(7)2)9-5-20-12(16-9)17-11(13)14/h4-5,15H,3H2,1-2H3,(H4,13,14,16,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against dog gastric proton-pump enzyme H+/K+ ATPase				J Med Chem 33: 543-52 (1990) BindingDB Entry DOI: 10.7270/Q2K35V79
					More data for this Ligand-Target Pair