BDBM50013516 2-{4-[2-(1H-Tetrazol-5-yl)-ethyl]-phenoxymethyl}-quinoline::CHEMBL18177

SMILES: C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)c1nnn[nH]1

InChI Key: InChIKey=IIHHSWYDPCUBAX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50013516 (2-{4-[2-(1H-Tetrazol-5-yl)-ethyl]-phenoxymethyl}-q...) Show SMILES C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)c1nnn[nH]1 Show InChI InChI=1S/C19H17N5O/c1-2-4-18-15(3-1)8-9-16(20-18)13-25-17-10-5-14(6-11-17)7-12-19-21-23-24-22-19/h1-6,8-11H,7,12-13H2,(H,21,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50013516 (2-{4-[2-(1H-Tetrazol-5-yl)-ethyl]-phenoxymethyl}-q...) Show SMILES C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)c1nnn[nH]1 Show InChI InChI=1S/C19H17N5O/c1-2-4-18-15(3-1)8-9-16(20-18)13-25-17-10-5-14(6-11-17)7-12-19-21-23-24-22-19/h1-6,8-11H,7,12-13H2,(H,21,22,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair