BDBM50013517 2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-quinoline::CHEMBL18558

SMILES: C(CCc1nnn[nH]1)COc1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=JRLYDKCKUUVXLK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50013517 (2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-...) Show SMILES C(CCc1nnn[nH]1)COc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H21N5O2/c1-2-9-20-16(6-1)11-12-17(22-20)15-28-19-8-5-7-18(14-19)27-13-4-3-10-21-23-25-26-24-21/h1-2,5-9,11-12,14H,3-4,10,13,15H2,(H,23,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50013517 (2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-...) Show SMILES C(CCc1nnn[nH]1)COc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H21N5O2/c1-2-9-20-16(6-1)11-12-17(22-20)15-28-19-8-5-7-18(14-19)27-13-4-3-10-21-23-25-26-24-21/h1-2,5-9,11-12,14H,3-4,10,13,15H2,(H,23,24,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair