BDBM50013517 2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-quinoline::CHEMBL18558
SMILES: C(CCc1nnn[nH]1)COc1cccc(OCc2ccc3ccccc3n2)c1
InChI Key: InChIKey=JRLYDKCKUUVXLK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cysteinyl leukotriene receptor 1 (GUINEA PIG) | BDBM50013517![]() (2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research Curated by ChEMBL | Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM) | J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50013517![]() (2-{3-[4-(1H-Tetrazol-5-yl)-butoxy]-phenoxymethyl}-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research Curated by ChEMBL | Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips. | J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM | |||||||||||
More data for this Ligand-Target Pair |