BDBM50013530 2-{4-Ethyl-3-[3-(1H-tetrazol-5-yl)-propoxy]-phenoxymethyl}-quinoline::CHEMBL18309

SMILES: CCc1ccc(OCc2ccc3ccccc3n2)cc1OCCCc1nnn[nH]1

InChI Key: InChIKey=JZKKFABLTBZDCS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50013530 (2-{4-Ethyl-3-[3-(1H-tetrazol-5-yl)-propoxy]-phenox...) Show SMILES CCc1ccc(OCc2ccc3ccccc3n2)cc1OCCCc1nnn[nH]1 Show InChI InChI=1S/C22H23N5O2/c1-2-16-10-12-19(14-21(16)28-13-5-8-22-24-26-27-25-22)29-15-18-11-9-17-6-3-4-7-20(17)23-18/h3-4,6-7,9-12,14H,2,5,8,13,15H2,1H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50013530 (2-{4-Ethyl-3-[3-(1H-tetrazol-5-yl)-propoxy]-phenox...) Show SMILES CCc1ccc(OCc2ccc3ccccc3n2)cc1OCCCc1nnn[nH]1 Show InChI InChI=1S/C22H23N5O2/c1-2-16-10-12-19(14-21(16)28-13-5-8-22-24-26-27-25-22)29-15-18-11-9-17-6-3-4-7-20(17)23-18/h3-4,6-7,9-12,14H,2,5,8,13,15H2,1H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.				J Med Chem 33: 1186-94 (1990) BindingDB Entry DOI: 10.7270/Q2TB15WM
					More data for this Ligand-Target Pair