BindingDB logo
myBDB logout

BDBM50013533 2-[4-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quinoline::CHEMBL19136

SMILES: C(Oc1ccc(Cc2nnn[nH]2)cc1)c1ccc2ccccc2n1

InChI Key: InChIKey=XFZHNLAPVOHWLM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50013533   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)
BDBM50013533
PNG
(2-[4-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quino...)
Show SMILES C(Oc1ccc(Cc2nnn[nH]2)cc1)c1ccc2ccccc2n1
Show InChI InChI=1S/C18H15N5O/c1-2-4-17-14(3-1)7-8-15(19-17)12-24-16-9-5-13(6-10-16)11-18-20-22-23-21-18/h1-10H,11-12H2,(H,20,21,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
275n/an/an/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)


J Med Chem 33: 1186-94 (1990)


BindingDB Entry DOI: 10.7270/Q2TB15WM
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50013533
PNG
(2-[4-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quino...)
Show SMILES C(Oc1ccc(Cc2nnn[nH]2)cc1)c1ccc2ccccc2n1
Show InChI InChI=1S/C18H15N5O/c1-2-4-17-14(3-1)7-8-15(19-17)12-24-16-9-5-13(6-10-16)11-18-20-22-23-21-18/h1-10H,11-12H2,(H,20,21,22,23)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.


J Med Chem 33: 1186-94 (1990)


BindingDB Entry DOI: 10.7270/Q2TB15WM
More data for this
Ligand-Target Pair