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BDBM50013538 4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid::CHEMBL18471

SMILES: OC(=O)CCCOc1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=HYTBIVFDTLBKQS-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50013538   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)
BDBM50013538
PNG
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Show SMILES OC(=O)CCCOc1cccc(OCc2ccc3ccccc3n2)c1
Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Similars

PubMed
130n/an/an/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung was determined using [3H]-LTD4 (0.2 nM)


J Med Chem 33: 1186-94 (1990)


BindingDB Entry DOI: 10.7270/Q2TB15WM
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50013538
PNG
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Show SMILES OC(=O)CCCOc1cccc(OCc2ccc3ccccc3n2)c1
Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
130n/an/an/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membrane


J Med Chem 33: 2828-41 (1990)


BindingDB Entry DOI: 10.7270/Q29C6WDM
More data for this
Ligand-Target Pair
Cysteinyl leukotriene receptor


(Homo sapiens (Human))
BDBM50013538
PNG
(4-[3-(Quinolin-2-ylmethoxy)-phenoxy]-butyric acid ...)
Show SMILES OC(=O)CCCOc1cccc(OCc2ccc3ccccc3n2)c1
Show InChI InChI=1S/C20H19NO4/c22-20(23)9-4-12-24-17-6-3-7-18(13-17)25-14-16-11-10-15-5-1-2-8-19(15)21-16/h1-3,5-8,10-11,13H,4,9,12,14H2,(H,22,23)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 240n/an/an/an/an/an/a



Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibition of the spasmogenic activity of LTD4 in guinea pig parenchymal strips.


J Med Chem 33: 1186-94 (1990)


BindingDB Entry DOI: 10.7270/Q2TB15WM
More data for this
Ligand-Target Pair