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BDBM50013717 CHEMBL3264548

SMILES: OC(=O)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1

InChI Key: InChIKey=GMRWCGDPKMVQCK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013717   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50013717
PNG
(CHEMBL3264548)
Show SMILES OC(=O)C1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1
Show InChI InChI=1S/C21H32N2O3/c24-21(25)19-9-14-23(15-10-19)17-18-5-7-20(8-6-18)26-16-4-13-22-11-2-1-3-12-22/h5-8,19H,1-4,9-17H2,(H,24,25)
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Similars
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Johann Wolfgang Goethe University

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK293 cells after 90 mins

Bioorg Med Chem Lett 24: 2236-9 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.098
BindingDB Entry DOI: 10.7270/Q2MP54TD
More data for this
Ligand-Target Pair