Found 8 hits for monomerid = 50013726 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Inhibition of human glucocorticoid receptor |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Thyroid hormone receptor beta
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Inhibition of human thyroid hormone receptor-beta |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Antagonist activity at GST-tagged PPAR-alpha (unknown origin) assessed as inhibition of GW7647-induced effect after 2 hrs by TR-FRET assay |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Antagonist activity at human PPAR-alpha assessed as inhibition of GW7647-induced effect after overnight incubation by cell-based luciferase reporter ... |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PPAR-gamma |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Estradiol receptor beta (ERβ)
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Inhibition of human estrogen receptor beta |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha (PPAR alpha)
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Agonist activity at human PPAR-alpha |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50013726
(CHEMBL3264932)Show SMILES CCn1c(CCCc2ccc(cc2)-c2ccc(NS(=O)(=O)c3ccccc3)cn2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C35H39N5O3S/c1-5-39-33(37-40(34(39)41)25-27-16-20-29(21-17-27)35(2,3)4)13-9-10-26-14-18-28(19-15-26)32-23-22-30(24-36-32)38-44(42,43)31-11-7-6-8-12-31/h6-8,11-12,14-24,38H,5,9-10,13,25H2,1-4H3 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description Inhibition of human PPAR-delta |
Bioorg Med Chem Lett 24: 2267-72 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33 |
More data for this Ligand-Target Pair | |