BDBM50013731 CHEMBL3264921

SMILES: CCn1c(CCCc2ccc(OC(C)(C)C(=O)NS(=O)(=O)c3ccc(cc3)C(C)C)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O

InChI Key: InChIKey=PDUADWDQQOEDHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50013731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50013731 (CHEMBL3264921) Show SMILES CCn1c(CCCc2ccc(OC(C)(C)C(=O)NS(=O)(=O)c3ccc(cc3)C(C)C)cc2)nn(Cc2ccc(cc2)C(C)(C)C)c1=O Show InChI InChI=1S/C37H48N4O5S/c1-9-40-33(38-41(35(40)43)25-28-13-19-30(20-14-28)36(4,5)6)12-10-11-27-15-21-31(22-16-27)46-37(7,8)34(42)39-47(44,45)32-23-17-29(18-24-32)26(2)3/h13-24,26H,9-12,25H2,1-8H3,(H,39,42)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Inception Sciences Curated by ChEMBL					Assay Description Antagonist activity at human PPAR-alpha assessed as inhibition of GW7647-induced effect after overnight incubation by cell-based luciferase reporter ...				Bioorg Med Chem Lett 24: 2267-72 (2014) Article DOI: 10.1016/j.bmcl.2014.03.090 BindingDB Entry DOI: 10.7270/Q2GX4D33
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