BDBM50014231 6-(2,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline::CHEMBL94508

SMILES: Clc1ccc(C2CN3CCCC3c3ccccc23)c(Cl)c1

InChI Key: InChIKey=INONMKPUSJMMRO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50014231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SLC6A3 (MOUSE)	BDBM50014231 (6-(2,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...) Show SMILES Clc1ccc(C2CN3CCCC3c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C18H17Cl2N/c19-12-7-8-14(17(20)10-12)16-11-21-9-3-6-18(21)15-5-2-1-4-13(15)16/h1-2,4-5,7-8,10,16,18H,3,6,9,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for serotonin(5-HT) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Norepinephrine transporter (MOUSE)	BDBM50014231 (6-(2,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...) Show SMILES Clc1ccc(C2CN3CCCC3c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C18H17Cl2N/c19-12-7-8-14(17(20)10-12)16-11-21-9-3-6-18(21)15-5-2-1-4-13(15)16/h1-2,4-5,7-8,10,16,18H,3,6,9,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for norepinephrine (NE) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair
Dopamine transporter (MOUSE)	BDBM50014231 (6-(2,4-Dichloro-phenyl)-1,2,3,5,6,10b-hexahydro-py...) Show SMILES Clc1ccc(C2CN3CCCC3c3ccccc23)c(Cl)c1 Show InChI InChI=1S/C18H17Cl2N/c19-12-7-8-14(17(20)10-12)16-11-21-9-3-6-18(21)15-5-2-1-4-13(15)16/h1-2,4-5,7-8,10,16,18H,3,6,9,11H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical Curated by ChEMBL					Assay Description Tested in vitro for dopamine(DA) neuronal uptake inhibition				J Med Chem 33: 2793-7 (1990) BindingDB Entry DOI: 10.7270/Q27S7PB4
					More data for this Ligand-Target Pair