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BDBM50015730 1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,6-tetrahydro-pyridine (HCl)::CHEMBL68156

SMILES: FC(F)(F)c1cccc(c1)C1(CCCCC1)N1CCC=CC1

InChI Key: InChIKey=JQKUSTCXZKCEAV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50015730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2C


(Rattus norvegicus (Rat))		BDBM50015730
PNG
(1-[1-(3-Trifluoromethyl-phenyl)-cyclohexyl]-1,2,3,...)
Show SMILES FC(F)(F)c1cccc(c1)C1(CCCCC1)N1CCC=CC1 |c:21|
Show InChI InChI=1S/C18H22F3N/c19-18(20,21)16-9-7-8-15(14-16)17(10-3-1-4-11-17)22-12-5-2-6-13-22/h2,5,7-9,14H,1,3-4,6,10-13H2
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 422n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Ability to displace [3H]- TCP from PCP receptor in tissue homogenate preparation of fresh whole rat brain minus cerebellum.

J Med Chem 33: 2211-5 (1990)


BindingDB Entry DOI: 10.7270/Q2BZ6515
More data for this
Ligand-Target Pair