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SMILES: Cl.Clc1ccc(CC(=O)N2CCNCC2COc2cccnc2)cc1

InChI Key: InChIKey=IDIVLLSKLUTDHS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016204   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50016204
PNG
(CHEMBL3262150)
Show SMILES Cl.Clc1ccc(CC(=O)N2CCNCC2COc2cccnc2)cc1
Show InChI InChI=1S/C18H20ClN3O2.ClH/c19-15-5-3-14(4-6-15)10-18(23)22-9-8-21-11-16(22)13-24-17-2-1-7-20-12-17;/h1-7,12,16,21H,8-11,13H2;1H
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Critical Therapeutics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysis

J Med Chem 57: 3966-83 (2014)


Article DOI: 10.1021/jm5004599
BindingDB Entry DOI: 10.7270/Q2CV4K8S
More data for this
Ligand-Target Pair