BDBM50016215 CHEMBL3262161

SMILES: Cl.CC(C)c1ccc(NC(=O)N2CCNCC2COc2cccnc2)cc1

InChI Key: InChIKey=RLGPWCBUEKATEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50016215 (CHEMBL3262161) Show SMILES Cl.CC(C)c1ccc(NC(=O)N2CCNCC2COc2cccnc2)cc1 Show InChI InChI=1S/C20H26N4O2.ClH/c1-15(2)16-5-7-17(8-6-16)23-20(25)24-11-10-22-12-18(24)14-26-19-4-3-9-21-13-19;/h3-9,13,15,18,22H,10-12,14H2,1-2H3,(H,23,25);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Critical Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysis				J Med Chem 57: 3966-83 (2014) Article DOI: 10.1021/jm5004599 BindingDB Entry DOI: 10.7270/Q2CV4K8S
					More data for this Ligand-Target Pair