BDBM50016219 CHEMBL3262165

SMILES: Cl.COc1cccc(NC(=O)N2CCNCC2COc2cccnc2)c1

InChI Key: InChIKey=LAXDTALIZUATTJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50016219 (CHEMBL3262165) Show SMILES Cl.COc1cccc(NC(=O)N2CCNCC2COc2cccnc2)c1 Show InChI InChI=1S/C18H22N4O3.ClH/c1-24-16-5-2-4-14(10-16)21-18(23)22-9-8-20-11-15(22)13-25-17-6-3-7-19-12-17;/h2-7,10,12,15,20H,8-9,11,13H2,1H3,(H,21,23);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Critical Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysis				J Med Chem 57: 3966-83 (2014) Article DOI: 10.1021/jm5004599 BindingDB Entry DOI: 10.7270/Q2CV4K8S
					More data for this Ligand-Target Pair