BDBM50016223 CHEMBL3262169

SMILES: Cl.FC(F)(F)Oc1ccc(NC(=O)N2CCNCC2COc2cccnc2)cc1

InChI Key: InChIKey=HAGIMNGTUWGKLD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50016223 (CHEMBL3262169) Show SMILES Cl.FC(F)(F)Oc1ccc(NC(=O)N2CCNCC2COc2cccnc2)cc1 Show InChI InChI=1S/C18H19F3N4O3.ClH/c19-18(20,21)28-15-5-3-13(4-6-15)24-17(26)25-9-8-23-10-14(25)12-27-16-2-1-7-22-11-16;/h1-7,11,14,23H,8-10,12H2,(H,24,26);1H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Critical Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of biotinylated alpha-bungarotoxin binding to alpha7 nAChR in rat PC12 cells by FACS analysis				J Med Chem 57: 3966-83 (2014) Article DOI: 10.1021/jm5004599 BindingDB Entry DOI: 10.7270/Q2CV4K8S
					More data for this Ligand-Target Pair