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SMILES: CC(C)C1=CC(=O)C(\C=N\OC(=O)c2ccccc2C)=CC1=O

InChI Key: InChIKey=KRHMAJOTJVOLBI-VXLYETTFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50016509   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase PLK1


(Homo sapiens (Human))		BDBM50016509
PNG
(CHEMBL3260250)
Show SMILES CC(C)C1=CC(=O)C(\C=N\OC(=O)c2ccccc2C)=CC1=O |c:20,t:3|
Show InChI InChI=1S/C18H17NO4/c1-11(2)15-9-16(20)13(8-17(15)21)10-19-23-18(22)14-7-5-4-6-12(14)3/h4-11H,1-3H3/b19-10+
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MMDB

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PC cid
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Article
PubMed
n/an/a 2.31E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of PLK1 (unknown origin) using RRRDELMEASFADQEAKV as substrate after 20 mins by liquid scintillation counting analysis

Eur J Med Chem 81: 420-6 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.026
BindingDB Entry DOI: 10.7270/Q2ZP47PK
More data for this
Ligand-Target Pair