BDBM50016670 2-(4-Benzyloxy-phenyl)-N-hydroxy-N-(3-phenyl-propyl)-acetamide::CHEMBL52241

SMILES: ON(CCCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=UTDJJMSBKPJRDE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50016670 (2-(4-Benzyloxy-phenyl)-N-hydroxy-N-(3-phenyl-propy...) Show SMILES ON(CCCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO3/c26-24(25(27)17-7-12-20-8-3-1-4-9-20)18-21-13-15-23(16-14-21)28-19-22-10-5-2-6-11-22/h1-6,8-11,13-16,27H,7,12,17-19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase (Rattus norvegicus)	BDBM50016670 (2-(4-Benzyloxy-phenyl)-N-hydroxy-N-(3-phenyl-propy...) Show SMILES ON(CCCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO3/c26-24(25(27)17-7-12-20-8-3-1-4-9-20)18-21-13-15-23(16-14-21)28-19-22-10-5-2-6-11-22/h1-6,8-11,13-16,27H,7,12,17-19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of rat platelet 12-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50016670 (2-(4-Benzyloxy-phenyl)-N-hydroxy-N-(3-phenyl-propy...) Show SMILES ON(CCCc1ccccc1)C(=O)Cc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO3/c26-24(25(27)17-7-12-20-8-3-1-4-9-20)18-21-13-15-23(16-14-21)28-19-22-10-5-2-6-11-22/h1-6,8-11,13-16,27H,7,12,17-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair