BDBM50016674 4-[Hydroxy-(4-phenyl-butyryl)-amino]-butyric acid ethyl ester::CHEMBL54438

SMILES: CCOC(=O)CCCN(O)C(=O)CCCc1ccccc1

InChI Key: InChIKey=BTQJWNYKTAAGQX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50016674 (4-[Hydroxy-(4-phenyl-butyryl)-amino]-butyric acid ...) Show SMILES CCOC(=O)CCCN(O)C(=O)CCCc1ccccc1 Show InChI InChI=1S/C16H23NO4/c1-2-21-16(19)12-7-13-17(20)15(18)11-6-10-14-8-4-3-5-9-14/h3-5,8-9,20H,2,6-7,10-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase (Rattus norvegicus)	BDBM50016674 (4-[Hydroxy-(4-phenyl-butyryl)-amino]-butyric acid ...) Show SMILES CCOC(=O)CCCN(O)C(=O)CCCc1ccccc1 Show InChI InChI=1S/C16H23NO4/c1-2-21-16(19)12-7-13-17(20)15(18)11-6-10-14-8-4-3-5-9-14/h3-5,8-9,20H,2,6-7,10-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of rat platelet 12-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50016674 (4-[Hydroxy-(4-phenyl-butyryl)-amino]-butyric acid ...) Show SMILES CCOC(=O)CCCN(O)C(=O)CCCc1ccccc1 Show InChI InChI=1S/C16H23NO4/c1-2-21-16(19)12-7-13-17(20)15(18)11-6-10-14-8-4-3-5-9-14/h3-5,8-9,20H,2,6-7,10-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair