BDBM50016676 CHEMBL293264::N-Hydroxy-4-(4-methoxy-phenyl)-N-phenethyl-butyramide

SMILES: COc1ccc(CCCC(=O)N(O)CCc2ccccc2)cc1

InChI Key: InChIKey=KQWFHBABTNKSHN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 12-lipoxygenase (Rattus norvegicus)	BDBM50016676 (CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...) Show SMILES COc1ccc(CCCC(=O)N(O)CCc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c1-23-18-12-10-17(11-13-18)8-5-9-19(21)20(22)15-14-16-6-3-2-4-7-16/h2-4,6-7,10-13,22H,5,8-9,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of rat platelet 12-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50016676 (CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...) Show SMILES COc1ccc(CCCC(=O)N(O)CCc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c1-23-18-12-10-17(11-13-18)8-5-9-19(21)20(22)15-14-16-6-3-2-4-7-16/h2-4,6-7,10-13,22H,5,8-9,14-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50016676 (CHEMBL293264 | N-Hydroxy-4-(4-methoxy-phenyl)-N-ph...) Show SMILES COc1ccc(CCCC(=O)N(O)CCc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c1-23-18-12-10-17(11-13-18)8-5-9-19(21)20(22)15-14-16-6-3-2-4-7-16/h2-4,6-7,10-13,22H,5,8-9,14-15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair