BDBM50016679 CHEMBL52085::N-Hydroxy-N-methyl-2-[3-(quinolin-2-ylmethoxy)-phenyl]-acetamide

SMILES: CN(O)C(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=DDUDJLAELMWWHY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50016679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 12-lipoxygenase (Rattus norvegicus)	BDBM50016679 (CHEMBL52085 | N-Hydroxy-N-methyl-2-[3-(quinolin-2-...) Show SMILES CN(O)C(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H18N2O3/c1-21(23)19(22)12-14-5-4-7-17(11-14)24-13-16-10-9-15-6-2-3-8-18(15)20-16/h2-11,23H,12-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of rat platelet 12-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50016679 (CHEMBL52085 | N-Hydroxy-N-methyl-2-[3-(quinolin-2-...) Show SMILES CN(O)C(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H18N2O3/c1-21(23)19(22)12-14-5-4-7-17(11-14)24-13-16-10-9-15-6-2-3-8-18(15)20-16/h2-11,23H,12-13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50016679 (CHEMBL52085 | N-Hydroxy-N-methyl-2-[3-(quinolin-2-...) Show SMILES CN(O)C(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H18N2O3/c1-21(23)19(22)12-14-5-4-7-17(11-14)24-13-16-10-9-15-6-2-3-8-18(15)20-16/h2-11,23H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase				J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21
					More data for this Ligand-Target Pair