BDBM50016686 CHEMBL54013::N-Hydroxy-3-phenyl-N-(3-phenyl-propyl)-propionamide
SMILES: ON(CCCc1ccccc1)C(=O)CCc1ccccc1
InChI Key: InChIKey=ZTZZZGWUAYORTE-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arachidonate 5-lipoxygenase (Rattus norvegicus) | BDBM50016686 (CHEMBL54013 | N-Hydroxy-3-phenyl-N-(3-phenyl-propy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research Curated by ChEMBL | Assay Description In vitro inhibition of rat polymorphonuclear leukocyte 5-lipoxygenase | J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 12-lipoxygenase (Rattus norvegicus) | BDBM50016686 (CHEMBL54013 | N-Hydroxy-3-phenyl-N-(3-phenyl-propy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research Curated by ChEMBL | Assay Description Invitro inhibition of rat platelet 12-lipoxygenase | J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arachidonate 5-lipoxygenase (Homo sapiens (Human)) | BDBM50016686 (CHEMBL54013 | N-Hydroxy-3-phenyl-N-(3-phenyl-propy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Rorer Central Research Curated by ChEMBL | Assay Description Invitro inhibition of polymorphonuclear leukocyte derived human 5-lipoxygenase | J Med Chem 32: 1836-42 (1989) BindingDB Entry DOI: 10.7270/Q2VT1R21 | |||||||||||
More data for this Ligand-Target Pair |