BDBM50017264 CHEMBL3287718
SMILES: CCCC(=O)c1ccc(OCCCCOc2c(OC)cccc2C(O)=O)c(C)c1O
InChI Key: InChIKey=JUJXMFHCVVWQIP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat)) | BDBM50017264![]() (CHEMBL3287718) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated... | J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50017264![]() (CHEMBL3287718) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 34 | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated... | J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (mGlu4) (Rattus norvegicus (Rat)) | BDBM50017264![]() (CHEMBL3287718) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGlu4 receptor expressed in HEK293 cells | J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor (RAT) | BDBM50017264![]() (CHEMBL3287718) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Antagonist activity at rat mGlu1 receptor expressed in HEK293 cells | J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9 | |||||||||||
More data for this Ligand-Target Pair |