BDBM50019140 CHEMBL3288756

SMILES: CC(C)N1C(=O)CN(C1=O)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=UDKYFCCRHLNGBQ-ZXGKGEBGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50019140 (CHEMBL3288756) Show SMILES CC(C)N1C(=O)CN(C1=O)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C25H29ClN2O7/c1-13(2)28-20(30)11-27(25(28)34)17-6-3-14(4-7-17)9-16-10-15(5-8-18(16)26)24-23(33)22(32)21(31)19(12-29)35-24/h3-8,10,13,19,21-24,29,31-33H,9,11-12H2,1-2H3/t19-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...				Bioorg Med Chem 22: 3414-22 (2014) Article DOI: 10.1016/j.bmc.2014.04.036 BindingDB Entry DOI: 10.7270/Q2H70HCT
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50019140 (CHEMBL3288756) Show SMILES CC(C)N1C(=O)CN(C1=O)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C25H29ClN2O7/c1-13(2)28-20(30)11-27(25(28)34)17-6-3-14(4-7-17)9-16-10-15(5-8-18(16)26)24-23(33)22(32)21(31)19(12-29)35-24/h3-8,10,13,19,21-24,29,31-33H,9,11-12H2,1-2H3/t19-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of [14C]-AMG uptake after 3 hrs by microbeta scintillation counting analysi...				Bioorg Med Chem 22: 3414-22 (2014) Article DOI: 10.1016/j.bmc.2014.04.036 BindingDB Entry DOI: 10.7270/Q2H70HCT
					More data for this Ligand-Target Pair