null

SMILES: NS(=O)(=O)c1ccc(NC(=O)Nc2cc(c(Cl)cc2Cl)S(N)(=O)=O)cc1

InChI Key: InChIKey=JYFQGBDESBWRFP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50019530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50019530 (CHEMBL3291098) Show SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2cc(c(Cl)cc2Cl)S(N)(=O)=O)cc1 Show InChI InChI=1S/C13H12Cl2N4O5S2/c14-9-5-10(15)12(26(17,23)24)6-11(9)19-13(20)18-7-1-3-8(4-2-7)25(16,21)22/h1-6H,(H2,16,21,22)(H2,17,23,24)(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50019530 (CHEMBL3291098) Show SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2cc(c(Cl)cc2Cl)S(N)(=O)=O)cc1 Show InChI InChI=1S/C13H12Cl2N4O5S2/c14-9-5-10(15)12(26(17,23)24)6-11(9)19-13(20)18-7-1-3-8(4-2-7)25(16,21)22/h1-6H,(H2,16,21,22)(H2,17,23,24)(H2,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50019530 (CHEMBL3291098) Show SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2cc(c(Cl)cc2Cl)S(N)(=O)=O)cc1 Show InChI InChI=1S/C13H12Cl2N4O5S2/c14-9-5-10(15)12(26(17,23)24)6-11(9)19-13(20)18-7-1-3-8(4-2-7)25(16,21)22/h1-6H,(H2,16,21,22)(H2,17,23,24)(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydra...				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50019530 (CHEMBL3291098) Show SMILES NS(=O)(=O)c1ccc(NC(=O)Nc2cc(c(Cl)cc2Cl)S(N)(=O)=O)cc1 Show InChI InChI=1S/C13H12Cl2N4O5S2/c14-9-5-10(15)12(26(17,23)24)6-11(9)19-13(20)18-7-1-3-8(4-2-7)25(16,21)22/h1-6H,(H2,16,21,22)(H2,17,23,24)(H2,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	573	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Inhibition of human cloned cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Eur J Med Chem 82: 47-55 (2014) Article DOI: 10.1016/j.ejmech.2014.05.039 BindingDB Entry DOI: 10.7270/Q2X63PH6
					More data for this Ligand-Target Pair