BDBM50019849 CHEMBL3286914

SMILES: O=C(OCCn1ccnc1-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1

InChI Key: InChIKey=FDQDAIHJWMJPDG-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50019849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Homo sapiens (Human))	BDBM50019849 (CHEMBL3286914) Show SMILES O=C(OCCn1ccnc1-c1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccccc1 Show InChI InChI=1S/C31H31N5O2/c37-30(38-22-21-34-20-17-32-29(34)25-11-5-2-6-12-25)26-15-18-35(19-16-26)31-33-27-13-7-8-14-28(27)36(31)23-24-9-3-1-4-10-24/h1-14,17,20,26H,15-16,18-19,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Binding affinity to His6-tagged PDE-delta (unknown origin) measured every 3 mins by fluorescence polarization assay				J Med Chem 57: 5435-48 (2014) Article DOI: 10.1021/jm500632s BindingDB Entry DOI: 10.7270/Q24Q7WJP
					More data for this Ligand-Target Pair