null
SMILES: Cc1[nH]n(C)c(=O)c1C(=N)c1cccc(Cl)c1
InChI Key: InChIKey=GQGIZIKPIPCGCO-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A) dopamine receptor (RAT) | BDBM50019913 (4-[(3-Chloro-phenyl)-imino-methyl]-2,5-dimethyl-2H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Affinity for displacement of [3H]-clonidine labeled Dopamine receptor D1 | J Med Chem 30: 1807-12 (1987) BindingDB Entry DOI: 10.7270/Q29K497N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50019913 (4-[(3-Chloro-phenyl)-imino-methyl]-2,5-dimethyl-2H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Affinity for displacement of [3H]-SCH-23,390 labeled Dopamine receptor D1 | J Med Chem 30: 1807-12 (1987) BindingDB Entry DOI: 10.7270/Q29K497N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50019913 (4-[(3-Chloro-phenyl)-imino-methyl]-2,5-dimethyl-2H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description Affinity for displacement of [3H]-WB-4101 labeled Dopamine receptor D1 | J Med Chem 30: 1807-12 (1987) BindingDB Entry DOI: 10.7270/Q29K497N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50019913 (4-[(3-Chloro-phenyl)-imino-methyl]-2,5-dimethyl-2H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by ChEMBL | Assay Description In vitro binding affinity against Dopamine receptor D2 by displacement of [3H]-haloperidol from rat striatal membranes. | J Med Chem 30: 1807-12 (1987) BindingDB Entry DOI: 10.7270/Q29K497N | |||||||||||
More data for this Ligand-Target Pair |