null

SMILES: Nc1n[nH]c2cccc(-c3ccc4N(CCOc4c3)C(=O)Nc3ccccc3)c12

InChI Key: InChIKey=DZTDIEVKRWPYNO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50020249   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020249 (CHEMBL3288527) Show SMILES Nc1n[nH]c2cccc(-c3ccc4N(CCOc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C22H19N5O2/c23-21-20-16(7-4-8-17(20)25-26-21)14-9-10-18-19(13-14)29-12-11-27(18)22(28)24-15-5-2-1-3-6-15/h1-10,13H,11-12H2,(H,24,28)(H3,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 in HUVEC assessed as inhibition of VEGF (1 to 165)-induced cell proliferation preincubated for 2 hrs followed by VEGF (1 to 165...				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50020249 (CHEMBL3288527) Show SMILES Nc1n[nH]c2cccc(-c3ccc4N(CCOc4c3)C(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C22H19N5O2/c23-21-20-16(7-4-8-17(20)25-26-21)14-9-10-18-19(13-14)29-12-11-27(18)22(28)24-15-5-2-1-3-6-15/h1-10,13H,11-12H2,(H,24,28)(H3,23,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) expressed in baculovirus expression system using poly (4 Glu, Tyr) as substrate after 60 mins by ELISA				ACS Med Chem Lett 5: 592-7 (2014) Article DOI: 10.1021/ml5000417 BindingDB Entry DOI: 10.7270/Q2TB18GG
					More data for this Ligand-Target Pair