BDBM50020269 (RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-acetic acid ethyl ester::CHEMBL38404::{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3-dihydro-benzo[e][1,4]diazepin-1-yl}-acetic acid ethyl ester

SMILES: CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1

InChI Key: InChIKey=UCQCEIZNVJVIKL-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50020269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125 I-gastrin from gastrin receptor of guinea pig gastric glands				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type A receptor in rat pancreas.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cortex.				Bioorg Med Chem Lett 3: 871-874 (1993) Article DOI: 10.1016/S0960-894X(00)80683-6 BindingDB Entry DOI: 10.7270/Q2513Z41
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125 I] CCK-8 from Cholecystokinin type A receptor of rat pancreas				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptor				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortex				J Med Chem 32: 13-6 (1989) BindingDB Entry DOI: 10.7270/Q2MC90MG
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50020269 ((RS)-{3-[3-(4-Chloro-phenyl)-ureido]-2-oxo-5-pheny...) Show SMILES CCOC(=O)CN1c2ccccc2C(=NC(NC(=O)Nc2ccc(Cl)cc2)C1=O)c1ccccc1 |c:14| Show InChI InChI=1S/C26H23ClN4O4/c1-2-35-22(32)16-31-21-11-7-6-10-20(21)23(17-8-4-3-5-9-17)29-24(25(31)33)30-26(34)28-19-14-12-18(27)13-15-19/h3-15,24H,2,16H2,1H3,(H2,28,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of binding of [125I]CCK-8 to cholecystokinin type A receptor in rat pancreatic tissue				J Med Chem 36: 4276-92 (1994) BindingDB Entry DOI: 10.7270/Q22J6CH9
					More data for this Ligand-Target Pair