BDBM50021196 2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexahydro-2H-11-oxa-4a-aza-benzo[a]fluoren-2-yl)-methyl-amide::CHEMBL48558
SMILES: CN(C1CCN2CCc3c(oc4ccccc34)C2C1)S(=O)(=O)CCO
InChI Key: InChIKey=KPPZSBMFUSDGBU-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
adrenergic Alpha2 (BOVINE) | BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) | PDB KEGG GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for its ability to displace [3H]-clonidine from alpha-2 adrenergic receptor of calf cerebral cortex | J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of hog kidney renin | J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cerebral cortex alpha adrenergic receptor (CALF) | BDBM50021196 (2-Hydroxy-ethanesulfonic acid (1,3,4,5,6,11b-hexah...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for its ability to displace [3H]-prazosin from alpha1-Adrenoreceptor of calf cerebral cortex | J Med Chem 28: 1756-9 (1986) BindingDB Entry DOI: 10.7270/Q2JW8CWS | |||||||||||
More data for this Ligand-Target Pair |