BDBM50021219 CHEMBL553648::[3-(2,4-Dichloro-phenyl)-indan-1-yl]-dimethyl-amine; hydrochloride
SMILES: CN(C)C1CC(c2ccccc12)c1ccc(Cl)cc1Cl
InChI Key: InChIKey=WVYAYEHQWAYJNS-UHFFFAOYSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of 5-HT uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of noradrenaline uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dopamine uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dopamine uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of noradrenaline uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50021219![]() (CHEMBL553648 | [3-(2,4-Dichloro-phenyl)-indan-1-yl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dopamine uptake in rat synaptosomal fraction | J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M | |||||||||||
More data for this Ligand-Target Pair |