BDBM50021561 CHEMBL3290585

SMILES: COc1ccc(Cl)cc1-c1nc(N)nc(n1)N1CCN(C)CC1

InChI Key: InChIKey=CLLDPKOCRQKNSX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50021561 (CHEMBL3290585) Show SMILES COc1ccc(Cl)cc1-c1nc(N)nc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C15H19ClN6O/c1-21-5-7-22(8-6-21)15-19-13(18-14(17)20-15)11-9-10(16)3-4-12(11)23-2/h3-4,9H,5-8H2,1-2H3,(H2,17,18,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...				Eur J Med Chem 83: 534-46 (2014) Article DOI: 10.1016/j.ejmech.2014.06.032 BindingDB Entry DOI: 10.7270/Q2W097HQ
					More data for this Ligand-Target Pair