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SMILES: CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(C)c(C)c1

InChI Key: InChIKey=CNTXJPIYOXOVSP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021567   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))		BDBM50021567
PNG
(CHEMBL3290591)
Show SMILES CN1CCN(CC1)c1nc(N)nc(n1)-c1ccc(C)c(C)c1
Show InChI InChI=1S/C16H22N6/c1-11-4-5-13(10-12(11)2)14-18-15(17)20-16(19-14)22-8-6-21(3)7-9-22/h4-5,10H,6-9H2,1-3H3,(H2,17,18,19,20)
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Similars
Article
PubMed
 834n/an/an/an/an/an/an/an/a



Jagiellonian University Medical College

Curated by ChEMBL


Assay Description
Displacement of [3H]-histamine from human histamine H4 receptor expressed in insect Sf9 cell membrane co-expressing Galphai2/Gbeta1gamma2 subunits af...

Eur J Med Chem 83: 534-46 (2014)


Article DOI: 10.1016/j.ejmech.2014.06.032
BindingDB Entry DOI: 10.7270/Q2W097HQ
More data for this
Ligand-Target Pair