BDBM50021632 CHEMBL3297751

SMILES: CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=XVRSZUZIZXSHAX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021632 (CHEMBL3297751) Show SMILES CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H24F3N3O2/c1-20(2,3)12-26-18(28)9-16-10-25-19(29)17-8-14(11-27(16)17)13-5-4-6-15(7-13)21(22,23)24/h4-8,11,16H,9-10,12H2,1-3H3,(H,25,29)(H,26,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	521	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair