BDBM50021636 CHEMBL3298817

SMILES: FC(F)(F)c1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCOCC3)n2c1

InChI Key: InChIKey=GUZJUXQQGHIDBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021636   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50021636 (CHEMBL3298817) Show SMILES FC(F)(F)c1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCOCC3)n2c1 Show InChI InChI=1S/C22H24F3N3O3/c23-22(24,25)17-3-1-2-15(8-17)16-9-19-21(30)27-12-18(28(19)13-16)10-20(29)26-11-14-4-6-31-7-5-14/h1-3,8-9,13-14,18H,4-7,10-12H2,(H,26,29)(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50021636 (CHEMBL3298817) Show SMILES FC(F)(F)c1cccc(c1)-c1cc2C(=O)NCC(CC(=O)NCC3CCOCC3)n2c1 Show InChI InChI=1S/C22H24F3N3O3/c23-22(24,25)17-3-1-2-15(8-17)16-9-19-21(30)27-12-18(28(19)13-16)10-20(29)26-11-14-4-6-31-7-5-14/h1-3,8-9,13-14,18H,4-7,10-12H2,(H,26,29)(H,27,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	838	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Curated by ChEMBL					Assay Description Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...				Bioorg Med Chem 21: 7364-80 (2013) Article DOI: 10.1016/j.bmc.2013.09.054 BindingDB Entry DOI: 10.7270/Q23F4R7S
					More data for this Ligand-Target Pair