BDBM50021763 4-Amino-3-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-6-yl)-butyric acid; hydrochloride::CHEMBL543481

SMILES: Cn1c2ccc(cc2oc1=O)C(CN)CC(O)=O

InChI Key: InChIKey=HZACUGJVISCLPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-B receptor 1/2 (Rattus norvegicus (Rat))	BDBM50021763 (4-Amino-3-(3-methyl-2-oxo-2,3-dihydro-benzooxazol-...) Show SMILES Cn1c2ccc(cc2oc1=O)C(CN)CC(O)=O Show InChI InChI=1S/C12H14N2O4/c1-14-9-3-2-7(4-10(9)18-12(14)17)8(6-13)5-11(15)16/h2-4,8H,5-6,13H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
					More data for this Ligand-Target Pair