BDBM50021795 (R,R+S,S) 1-(3-Mercapto-2-methyl-propionyl)-octahydro-indole-2-carboxylic acid::(R,S+S,R) 1-(3-Mercapto-2-methyl-propionyl)-octahydro-indole-2-carboxylic acid::(S,S)1-(3-Mercapto-2-methyl-propionyl)-octahydro-indole-2-carboxylic acid::CHEMBL176763
SMILES: CC(CS)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O
InChI Key: InChIKey=ONOCQFIXOZOPIL-KQFSYOIOSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50021795![]() ((R,R+S,S) 1-(3-Mercapto-2-methyl-propionyl)-octahy...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate. | J Med Chem 30: 992-8 (1987) BindingDB Entry DOI: 10.7270/Q29C6Z02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50021795![]() ((R,R+S,S) 1-(3-Mercapto-2-methyl-propionyl)-octahy...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate. | J Med Chem 30: 992-8 (1987) BindingDB Entry DOI: 10.7270/Q29C6Z02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50021795![]() ((R,R+S,S) 1-(3-Mercapto-2-methyl-propionyl)-octahy...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate. | J Med Chem 30: 992-8 (1987) BindingDB Entry DOI: 10.7270/Q29C6Z02 | |||||||||||
More data for this Ligand-Target Pair |