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SMILES: Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=AWYHXTJQEWRWOA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50021810
PNG
(CHEMBL3299099)
Show SMILES Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C24H29ClN4O2S/c1-15-14-16(2)28-23-19(15)20(26)21(32-23)22(30)27-10-3-11-29-12-8-24(31,9-13-29)17-4-6-18(25)7-5-17/h4-7,14,31H,3,8-13,26H2,1-2H3,(H,27,30)
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Similars
Article
PubMed
 1.70E+3n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysis

J Med Chem 57: 4924-39 (2014)


Article DOI: 10.1021/jm500457x
BindingDB Entry DOI: 10.7270/Q29Z96FS
More data for this
Ligand-Target Pair