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SMILES: Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=MWEMZAUJQVTCGX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50021811   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50021811
PNG
(CHEMBL3298200)
Show SMILES Cc1cc(C)c2c(N)c(sc2n1)C(=O)NCCCCN1CCC(O)(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C25H31ClN4O2S/c1-16-15-17(2)29-24-20(16)21(27)22(33-24)23(31)28-11-3-4-12-30-13-9-25(32,10-14-30)18-5-7-19(26)8-6-18/h5-8,15,32H,3-4,9-14,27H2,1-2H3,(H,28,31)
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Article
PubMed
 2.25E+3n/an/an/an/an/an/an/an/a



Monash University

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysis

J Med Chem 57: 4924-39 (2014)


Article DOI: 10.1021/jm500457x
BindingDB Entry DOI: 10.7270/Q29Z96FS
More data for this
Ligand-Target Pair