Found 3 hits for monomerid = 50021867 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50021867
(CHEMBL3298327)Show SMILES CCOc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1 |r| Show InChI InChI=1S/C27H29N3O4/c1-2-34-21-9-7-20(8-10-21)29-19-5-3-18(4-6-19)15-16-28-17-25(32)22-11-13-24(31)27-23(22)12-14-26(33)30-27/h3-14,25,28-29,31-32H,2,15-17H2,1H3,(H,30,33)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]dihydroalprenolol from human beta2 adrenergic receptor expressing cell membrane by competition binding assay |
Bioorg Med Chem Lett 24: 2871-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.095 BindingDB Entry DOI: 10.7270/Q22J6DFT |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50021867
(CHEMBL3298327)Show SMILES CCOc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1 |r| Show InChI InChI=1S/C27H29N3O4/c1-2-34-21-9-7-20(8-10-21)29-19-5-3-18(4-6-19)15-16-28-17-25(32)22-11-13-24(31)27-23(22)12-14-26(33)30-27/h3-14,25,28-29,31-32H,2,15-17H2,1H3,(H,30,33)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Agonist activity at human beta2 adrenergic receptor expressed in cells by cAMP accumulation assay |
Bioorg Med Chem Lett 24: 2871-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.095 BindingDB Entry DOI: 10.7270/Q22J6DFT |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50021867
(CHEMBL3298327)Show SMILES CCOc1ccc(Nc2ccc(CCNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1 |r| Show InChI InChI=1S/C27H29N3O4/c1-2-34-21-9-7-20(8-10-21)29-19-5-3-18(4-6-19)15-16-28-17-25(32)22-11-13-24(31)27-23(22)12-14-26(33)30-27/h3-14,25,28-29,31-32H,2,15-17H2,1H3,(H,30,33)/t25-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Theravance, Inc.
Curated by ChEMBL
| Assay Description Agonist activity at human beta2 adrenergic receptor in human BEAS-2B cells by cAMP accumulation assay |
Bioorg Med Chem Lett 24: 2871-6 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.095 BindingDB Entry DOI: 10.7270/Q22J6DFT |
More data for this Ligand-Target Pair | |