BDBM50022107 CHEMBL3298226

SMILES: COc1cccc2ccnc(NCC(C)(C)c3ccccc3)c12

InChI Key: InChIKey=WZDLNTAETYKZDN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50022107 (CHEMBL3298226) Show SMILES COc1cccc2ccnc(NCC(C)(C)c3ccccc3)c12 Show InChI InChI=1S/C20H22N2O/c1-20(2,16-9-5-4-6-10-16)14-22-19-18-15(12-13-21-19)8-7-11-17(18)23-3/h4-13H,14H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition of current				Bioorg Med Chem Lett 24: 3018-22 (2014) Article DOI: 10.1016/j.bmcl.2014.05.035 BindingDB Entry DOI: 10.7270/Q2HH6MNP
					More data for this Ligand-Target Pair