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BDBM50022825 CHEMBL3298098

SMILES: COc1c(I)cc(I)cc1C(=O)N(C)c1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=NNDJLHXBJAFOGL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022825   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chitinase


(Onchocerca volvulus)		BDBM50022825
PNG
(CHEMBL3298098)
Show SMILES COc1c(I)cc(I)cc1C(=O)N(C)c1ccc(Oc2ccccc2)cc1
Show InChI InChI=1S/C21H17I2NO3/c1-24(21(25)18-12-14(22)13-19(23)20(18)26-2)15-8-10-17(11-9-15)27-16-6-4-3-5-7-16/h3-13H,1-2H3
UniProtKB/TrEMBL

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.71E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...

J Med Chem 57: 5792-9 (2014)


Article DOI: 10.1021/jm5006435
BindingDB Entry DOI: 10.7270/Q23B61Q3
More data for this
Ligand-Target Pair