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BDBM50022842 CHEMBL3298105

SMILES: Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2cccc(Cl)c2)cc1

InChI Key: InChIKey=ZGJYSGRERINDDW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022842   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Chitinase


(Onchocerca volvulus)		BDBM50022842
PNG
(CHEMBL3298105)
Show SMILES Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2cccc(Cl)c2)cc1
Show InChI InChI=1S/C19H12ClI2NO3/c20-11-2-1-3-15(8-11)26-14-6-4-13(5-7-14)23-19(25)16-9-12(21)10-17(22)18(16)24/h1-10,24H,(H,23,25)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.74E+3n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...

J Med Chem 57: 5792-9 (2014)


Article DOI: 10.1021/jm5006435
BindingDB Entry DOI: 10.7270/Q23B61Q3
More data for this
Ligand-Target Pair