BDBM50022887 CHEMBL3298108

SMILES: COc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1

InChI Key: InChIKey=LSZPGMLJSBNNPG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50022887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chitinase (Onchocerca volvulus)	BDBM50022887 (CHEMBL3298108) Show SMILES COc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C18H13I2NO2/c1-23-17-15(9-13(19)10-16(17)20)18(22)21-14-7-6-11-4-2-3-5-12(11)8-14/h2-10H,1H3,(H,21,22)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 mins by micr...				J Med Chem 57: 5792-9 (2014) Article DOI: 10.1021/jm5006435 BindingDB Entry DOI: 10.7270/Q23B61Q3
					More data for this Ligand-Target Pair