BDBM50023010 4-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-ethoxymethyl]-benzoic acid isopropyl ester::CHEMBL38988

SMILES: COc1ccc(COCC(Cn2ccnc2)OCc2ccc(cc2)C(=O)OC(C)C)cc1

InChI Key: InChIKey=RALRKFAWSGCMRN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50023010 (4-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-e...) Show SMILES COc1ccc(COCC(Cn2ccnc2)OCc2ccc(cc2)C(=O)OC(C)C)cc1 Show InChI InChI=1S/C25H30N2O5/c1-19(2)32-25(28)22-8-4-21(5-9-22)16-31-24(14-27-13-12-26-18-27)17-30-15-20-6-10-23(29-3)11-7-20/h4-13,18-19,24H,14-17H2,1-3H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibitory activity against intact human platelet TXA2 formation				J Med Chem 30: 1588-95 (1987) BindingDB Entry DOI: 10.7270/Q20R9NDV
					More data for this Ligand-Target Pair