BDBM50023015 4-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-ethoxymethyl]-benzamide::CHEMBL290637

SMILES: COc1ccc(COCC(Cn2ccnc2)OCc2ccc(cc2)C(N)=O)cc1

InChI Key: InChIKey=NEHYSCKOVZXSOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50023015 (4-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-e...) Show SMILES COc1ccc(COCC(Cn2ccnc2)OCc2ccc(cc2)C(N)=O)cc1 Show InChI InChI=1S/C22H25N3O4/c1-27-20-8-4-17(5-9-20)13-28-15-21(12-25-11-10-24-16-25)29-14-18-2-6-19(7-3-18)22(23)26/h2-11,16,21H,12-15H2,1H3,(H2,23,26)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibitory activity against intact human platelet TXA2 formation				J Med Chem 30: 1588-95 (1987) BindingDB Entry DOI: 10.7270/Q20R9NDV
					More data for this Ligand-Target Pair