BDBM50023018 4-[3-Imidazol-1-yl-2-(4-methoxy-benzyloxy)-propoxymethyl]-benzoic acid ethyl ester::CHEMBL290617

SMILES: CCOC(=O)c1ccc(COCC(Cn2ccnc2)OCc2ccc(OC)cc2)cc1

InChI Key: InChIKey=HLMWGRWOEPJLJP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50023018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50023018 (4-[3-Imidazol-1-yl-2-(4-methoxy-benzyloxy)-propoxy...) Show SMILES CCOC(=O)c1ccc(COCC(Cn2ccnc2)OCc2ccc(OC)cc2)cc1 Show InChI InChI=1S/C24H28N2O5/c1-3-30-24(27)21-8-4-19(5-9-21)15-29-17-23(14-26-13-12-25-18-26)31-16-20-6-10-22(28-2)11-7-20/h4-13,18,23H,3,14-17H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for inhibitory activity against intact human platelet TXA2 formation				J Med Chem 30: 1588-95 (1987) BindingDB Entry DOI: 10.7270/Q20R9NDV
					More data for this Ligand-Target Pair