null

SMILES: CC(N)Cc1cc2CCNc2cc1C

InChI Key: InChIKey=KMDNCNZLZNDTAF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50025078 (1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1cc2CCNc2cc1C Show InChI InChI=1S/C12H18N2/c1-8-5-12-10(3-4-14-12)7-11(8)6-9(2)13/h5,7,9,14H,3-4,6,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibition of DA uptake at dopamine uptake site				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50025078 (1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1cc2CCNc2cc1C Show InChI InChI=1S/C12H18N2/c1-8-5-12-10(3-4-14-12)7-11(8)6-9(2)13/h5,7,9,14H,3-4,6,13H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of NE uptake at NE uptake site				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025078 (1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1cc2CCNc2cc1C Show InChI InChI=1S/C12H18N2/c1-8-5-12-10(3-4-14-12)7-11(8)6-9(2)13/h5,7,9,14H,3-4,6,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A/B (Rattus norvegicus (rat))	BDBM50025078 (1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1cc2CCNc2cc1C Show InChI InChI=1S/C12H18N2/c1-8-5-12-10(3-4-14-12)7-11(8)6-9(2)13/h5,7,9,14H,3-4,6,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of MAO by using [14C]phenylethylamine as substrate in rat brain mitochondrial preparation				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50025078 (1-Methyl-2-(6-methyl-2,3-dihydro-1H-indol-5-yl)-et...) Show SMILES CC(N)Cc1cc2CCNc2cc1C Show InChI InChI=1S/C12H18N2/c1-8-5-12-10(3-4-14-12)7-11(8)6-9(2)13/h5,7,9,14H,3-4,6,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of Serotonin transporter uptake at serotonin uptake site				J Med Chem 29: 1406-12 (1986) BindingDB Entry DOI: 10.7270/Q29022S9
					More data for this Ligand-Target Pair